All living cells, regardless of type, communicate with their neighbors. When the body needs to direct healing, repair, or regeneration, it packages the instructions — signaling proteins, lipids, and nucleic acids — inside a membrane-bound extracellular vesicle small enough to travel through tissue fluid and blood.
Once released, an exosome does one of two things: it empties its cargo into the surrounding extracellular fluid, or it docks directly onto a recipient cell and delivers its payload inside. This mode of communication is called paracrine signaling, and it’s how the body coordinates immune balance, tissue repair, and vascular growth.